In a “Nature Communications” paper researchers of the Allain lab (IBC) describe an NMR-based approach to characterize molecular condensates without the need to tag or otherwise label the involved…
Press Release University of Bern / Medienmitteilung Universität Bern Researchers at the University of Bern, together with scientists from Stanford University and the European Molecular Biology…
The Nowacki lab wrote a review on “Functions and mechanisms of eukaryotic RNA-guided programmed DNA elimination” published in Biochemical Society Transactions. A focus is the elimination of DNA…
The Leidel and Steinmetz labs discovered that the relative levels of the mRNA modification m6A and the tRNA modification mcm5s2U control the degradation rate of m6A modified mRNAs. Codons bearing the…
Telomeres are known to be an extra sensitive cellular structure regarding damage caused by oxidation which can lead to premature cellular senescence. The Lingner and Doksani labs used a method to…
ETH News Article / ArtikelResearchers at ETH Zurich have unravelled the complex network that cells use to repair their genetic material. By examining thousands upon thousands of genetic interactions,…
Much remains too be learned about the function of circular RNAs, which are particulary enriched in neurons. The Schratt lab through the use of siRNAs performed a functional screen on pre-selected…
Press Release / Medienmitteilung Universität BernResearchers at the University of Bern have analyzed a mechanism by which the coronavirus manipulates human cells to replicate itself. They show that a…
TDP-43 is a major protein player in the pathology of amyothropic lateral sclerosis (ALS) through gain of pathogenic function and pathogenesis induced by loss of its normal function, which involves…