Welcome to the Swiss National Center
of Competence in Research RNA & Disease

The role of RNA in disease mechanisms

News

04/11/2022

Welcome to Franka Voigt!

Welcome to Franka Voigt as a new associate member of the NCCR RNA & Disease!

03/11/2022

Structural Analysis of Cas9 off-targeting

The Jinek lab together with the Allain, Palermo labs and scientists from Caribou Biosciences investigated the off-target…

01/11/2022

Register now & submit abstracts for the Swiss RNA Workshop 2023

The next Swiss RNA Workshop is scheduled to take place on Friday, January 27, 2023 in Bern starting at 09:15. The…

01/11/2022

Welcome to Rodrigo Reis!

Welcome to Rodrigo Reis as a new associate member of the NCCR RNA & Disease!

31/10/2022

NCCR RNA & Disease Newsletter The Messenger No.17

The seventeenth edition of the NCCR RNA & Disease Newsletter -The Messenger has been published.

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The central molecule of life

RNA functions as a carrier of genetic information, as a biocatalyst, and exerts crucial regulatory functions in the cell. Arrows indicate the flow of genetic information and regulatory functions.

molecool.ch - our public window on researching rna

Events

05 December 2022 16:30 – 17:30

Clotilde Lagier-Tourenne - NCCR Seminar Series (BE)

DCBP U113, University of Bern

06 December 2022 16:00 – 17:00

Clotilde Lagier-Tourenne - NCCR Seminar Series (ZH)

Y24-G-55 , University of Zurich

All events

Recent Publications

Structural basis for the assembly of the type V CRISPR-associated transposon complex
Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis
Differential phosphorylation of Clr4SUV39H by Cdk1 accompanies a histone H3 methylation switch that is essential for gametogenesis
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response
SARS-CoV-2 variant AlPLpha has a spike-dependent replication advantage over the ancestral B.1 strain in human cells with low ACE2 expression

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Recent Preprints

One for all – Human kidney Caki-1 cells are highly susceptible to infection with corona- and other respiratory viruses
Molecular basis of the TRAP complex function in ER protein biogenesis
Nirmatrelvir-resistant SARS-CoV-2 is efficiently transmitted in Syrian hamsters
A rapid protocol for ribosome profiling of low input samples
Pharmacological inhibition of bromodomain and extra-terminal proteins induces NRF-2-mediated inhibition of SARS-CoV-2 replication and is subject to viral antagonism