National Center of Competence
in Research, RNA & Disease

Welcome to the Swiss National Center
of Competence in Research RNA & Disease

The role of RNA in disease mechanisms

News

Molecular Insights into Assembly and Structure of a CRISPR-Associated Transposon System

CRISRP-associated transpososon (CAST) systems can be used as genetic engineering tools to insert site-specifically large…
 

How a Protease Regulates Argonaute Levels

In wild-type conditions, the Argonaute protein ALG-1 takes care of most miRNA-mediated functions with a small…
 

Regulating a Modulator of Cancer

The human non-coding RNA vtRNA1-1 modulates several processes which are important for cancer cells. However, how the…
 

How to Protect the tRNA Ligase Complex from Oxidation

The Jinek lab in collaboration with the Martinez lab and the Leitner group elucidated the mechanism how the human tRNA…
 

Finding Metadata From The Source Data: Illumina RNA-Seq

The Sequence Read Archive is an important repository for sequencing data. Metadata for sequencing datasets need to…
 

C-terminal amides mark proteins for degradation via SCF–FBXO31

A recent “Nature” paper by the groups of Jacob Corn (IMHS, D-BIOL) and Jeffrey Bode (D-CHAB) reveals how cells remove…
 
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