National Center of Competence
in Research, RNA & Disease

Welcome to the Swiss National Center
of Competence in Research RNA & Disease

The role of RNA in disease mechanisms

News

Translational Regulation of Hexokinase2 Expression Links Obesity and Hyperglycemia

Diabetes and fatty liver disease can be caused by hyperglycemia which in turn can be caused by obesity. However, the…
 

PIWI Slicing Differs In Vivo and In Vitro

The Pillai lab found that in vivo mouse MIWI cleaves targets containing mismatches at certain positions while in vitro…
 

TORC1 Activates Dormant Ribosomes

When nutrients are limited, cells keep a pool of dormant ribosomes which get activated, when nutrients become available…
 

Non-Metozoan Developmental mRNA Degradation Pathway Discovered

The ciliate Paramecium tetraurelia's genome enodes many PIWI-clade proteins, of many of which the function is unkown.…
 

Future Directions for Oligonucleotide Therapeutics Chemistry

Jonathan Hall wrote a perspective article which in his view the future directions for medicinal chemistry in the field…