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The Ruepp lab together with the Barabino, Dormann and Mühlemann labs determined the different protein and RNA interactome of soluble and phase-speparated FUS. Their findings have been published in Nucleic Acids in an article entitled "The phase separation-dependent FUS interactome reveals nuclear…

The NCCR RNA & Disease is participating in the #NCCRWomen campaign and will publish five portraits featuring researchers from our network this week!

The campaign in short: To celebrate the 50th anniversary of women obtaining the right to vote in Switzerland, all NCCRs currently in place across the…

Using an enhancer screen the Bühler identified new suppressors of RNA-mediated epigentic silencers. Their findings were published in PLOS Genetics in an article entitled "An enhancer screen identifies new suppressors of small-RNA-mediated epigenetic gene silencing".

Author summary
Besides silencing…

The Roignant and Soller labs in collaboration with other groups including the Jinek lab found that the E3 ubiquitin ligase Hakai stabilizes the m⁶A methylation machinery. Their article entitled "Hakai is required for stabilization of core components of the m6A mRNA methylation machinery" has been…

Using Cryo-EM, the Ban lab could visualize eight assembly intermediates of the human mitochondrial large ribosomal subunit and determined molecular structures for three of these. Their findings were published in Nature Communications in an article with the title "Stepwise maturation of the peptidyl…