The lab of Magdalini Polymenidou (University of Zurich) has just published a study in Nature, in which they describe a new model of human neural networks to study neurodegenerative diseases. Using this model, they were able to identify NPTX2, a new…

Stefanie Jonas is the 2024 recipient of the Eliza Izaurralde Award for Innovation in Research, Teaching and Service by the RNA Society. Congratulations!!!

We are pleased to announce the 2nd edition of the Swiss RNA Therapeutics Summit on January 25, 2024, at the University of Bern.

Link to the current program.Link to the list of current speakers & panelists. Link to registration.

The keynotes will…

A "Nature Communications" paper by five ETHZ groups reported an approach for the integrative structure determination of protein RNA complexes containing flexible regions, resulting in several conformations. This approach revealed that PTBP1 acts as a…

The Chao lab wrote a review "Following the Birth, Life, and Death of mRNAs in Single Cells" published in Annual Review of Cell and Developmental Biology, in which they discuss single-molecule techniques to follow the life cycle of an mRNA and the…

The Nowacki lab investigated the role played by Structural Maintenance of Chromosome (SMC) proteins in genome rearrangment in ciliates. Out of these group of ATPases the protein SMC4-2 is required for genome rearrangement while its paralog SMC4-1 is…

The next Swiss RNA Workshop is scheduled to take place on Friday, January 26, 2024 in Bern starting at 09:15. The workshop will be at the UniS building of the University of Bern, which is located in close proximity to the Bern train station.

The…

The lab of Jonatahan Hall and collaborators investigated the delivery, cellullar localization and activity of Antisense Oligonucleotides with different peptide conjugates and under different conditions using SSOs developed to induce splice switching…

In a "Nature Communications" paper, the Allain lab (IBC) with the Panse and Robinson groups (UZH) elucidated with a new method the in vivo RNA targets of NPL3, solved the structure of its RRMs with RNA, and then based on this knowledge could show…

Type III CRISPR-Cas systems can activate via second messengers ancyllary effector proteins. Type The Jinek lab using crystallography and biochemical experiments could now shed light on the molecular mechanism of the anillary nuclease Can2. Their…