The Lingner lab could shed further light on the functions of long noncoding RNA Telomeric repeat containing RNAs (TERRA). At telomeres, TERRA basepairs with DNA to form R-Loops, whose formation could now be shown depend on the DNA recombinase RAD51…
Mycobacterium tuberculosis is the biggest bacterial killer and new treatment options are needed due to the emergence of resistant strains. The Sander lab previously conducted a screen for novel compounds to block M. tuberculosis, one of the…
We warmly congratulate Raphaëlle Luisier on her appointment as Assistant Professor Tenure Track for Omics Data Science for Transcriptomics at the Department for BioMedical Research (DBMR), University of Bern!
We would like to congratulate Magdalini Polymenidou, who is Associate Professor of Biomedicine at the Department of Quantitative Biomedicine of the University of Zurich, on being elected Member of the European Molecular Biology Organization (EMBO)!…
The Karousis and Mühlemann labs developed based on dual centrifugation an efficient cell-free translation system for diverse human cells. They investigated several parameters in their protocol to assess their impact on the activity of the cell-free…
In a “Nature Communications” paper researchers of the Allain lab (IBC) describe an NMR-based approach to characterize molecular condensates without the need to tag or otherwise label the involved molecules. Besides eliminating alteration of results…
Press Release University of Bern / Medienmitteilung Universität Bern Researchers at the University of Bern, together with scientists from Stanford University and the European Molecular Biology Laboratory (EMBL), have discovered a new cellular…
The Nowacki lab wrote a review on “Functions and mechanisms of eukaryotic RNA-guided programmed DNA elimination” published in Biochemical Society Transactions. A focus is the elimination of DNA guided by complementary small RNAs, for which the…
The Leidel and Steinmetz labs discovered that the relative levels of the mRNA modification m6A and the tRNA modification mcm5s2U control the degradation rate of m6A modified mRNAs. Codons bearing the m6A modification lead to a slow down of…
