Welcome to Abdullah Kahraman as a new associate member of the NCCR RNA & Disease!

The Jeker lab wrote a review on Cellular Therapy and miRNAs including an experimental example of how overexpression of a specific miRNA in naive T cells makes them resistant to calcineurin inhibitors. The publication "Leveraging microRNAs for…

In a "Nature Communications" paper, the Allain (ETH Zurich), Campagne (University of Bordeaux, France) and Ruepp (King’s College London, UK) groups report that the RBM39 protein autoregulates itself through regulation of a poison exon. Altering this…

Multiple human genetic diseases are caused by premature stop codons located in the messenger RNA, inducing the ribosome to translate over these would be a promising approach to treat these diseases. Researcher from Novartis and the Mühlemann…

This year's Scientifica ran under the theme "What holds the world together" and over 20'000 people visited the exhibition on September 2 and 3 at the three venues of ETHZ and the University of Zurich. The NCCR RNA & Disease presented a booth with the…

The Stoffel lab and collaborators investigated the role of fructose metabolism and the rate limiting enzyme involved therein, called ketohexokinase. They could show that a fructose containing diet worsened pancreatic cancer progression in a  mouse…

The Stoffel lab aimed to shed light on the hetergenity displayed by pancreatic Beta cells during metabolic stress. They applied several high throughput sequencing methods combined with real-time imagining to characterize the stress response of B…

Cells need to be able to remove and degrade proteins which are no longer needed, the Schneider lab and collaborators could now obtain new insights how removal of proteins from the outer mitochondrial membrane of trypansomes work. Several proteins…

ETH News Article / Artikel

ETH Zurich molecular biologist Mandy Boontanrart is researching gene therapies that could be used to cure two of the most common types of inherited anaemia. She has now developed a promising approach for so-called…

The Kutay lab and collaborators investigated the disassembly of Nuclear Pore Complexes (NPCs) during mitosis, specifically what happens to the nuclear and cytoplasmic rings of the NPCs, which are built of Y-complexes. While most of the Y-complexes…