Rotem Karni - NCCR RNA Seminar Series (ZH)

LLPS REDIFINE allows the biophysical characterization of multicomponent condensates without tags or labels
ZNF574 is a quality control factor for defective ribosome biogenesis intermediates
RNA modifications tune m⁶A-dependent mRNA decay
Functions and mechanisms of eukaryotic RNA-guided programmed DNA elimination
Cyanobacterial Argonautes and Cas4 family nucleases cooperate to interfere with invading DNA

Recent Preprints

The 18S rRNA methyltransferase, BUD23, is required for appropriate lipid and mitochondrial metabolism
Beyond a Linear Structure: The Tubular Organization of the Tripartite Attachment Complex and the Functional Role of TAC53
Pus7 mutation links tRNA dysregulation to aggressive behavior through activation of the integrated stress response and glycolytic reprogramming
Newton's cradle-like allosteric mechanism explains regulatory RsmE RNA binding
Single-mRNA imaging and modeling reveal coupled translation initiation and elongation rates