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Publications

Most Recent

    • A.J. Gruber, F. Gypas, A. Riba, R. Schmidt and M. Zavolan (2018) Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms Nat Methods Epub ahead of print
      Pubmed
    • M. Mendel, K. M. Chen, D. Homolka, P. Gos, R.R. Pandey, A. A. McCarthy and R. S. Pillai (2018) Methylation of Structured RNA by the m(6)A Writer METTL16 Is Essential for Mouse Embryonic Development  Mol Cell Epub ahead of print
      Pubmed
    • D. J. F. Ramrath, M. Niemann, M. Leibundgut, P. Bieri, C. Prange, E.K. Horn, A. Leitner, D. Boehringer, A. Schneider and N. Ban (2018) Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes Science Epub ahead of print
      Pubmed
    • S. Schütz, E. Michel, F. F. Damberger, M. Oplová, C. Peña, A. Leitner, R. Aebersold, F.H. Allain and V.G.Panse (2018) Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2 Nat Commun 9(1), 3669
      Pubmed
    • M. Zavolan and A. P. Gerber (2018) Mirroring the multifaceted role of RNA and its partners in gene expression FEBS Lett 592(17), 2825-2827
      Pubmed

    2018

    • A.J. Gruber, F. Gypas, A. Riba, R. Schmidt and M. Zavolan (2018) Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms Nat Methods Epub ahead of print
      Pubmed
    • M. Mendel, K. M. Chen, D. Homolka, P. Gos, R.R. Pandey, A. A. McCarthy and R. S. Pillai (2018) Methylation of Structured RNA by the m(6)A Writer METTL16 Is Essential for Mouse Embryonic Development  Mol Cell Epub ahead of print
      Pubmed
    • D. J. F. Ramrath, M. Niemann, M. Leibundgut, P. Bieri, C. Prange, E.K. Horn, A. Leitner, D. Boehringer, A. Schneider and N. Ban (2018) Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes Science Epub ahead of print
      Pubmed
    • S. Schütz, E. Michel, F. F. Damberger, M. Oplová, C. Peña, A. Leitner, R. Aebersold, F.H. Allain and V.G.Panse (2018) Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2 Nat Commun 9(1), 3669
      Pubmed
    • M. Zavolan and A. P. Gerber (2018) Mirroring the multifaceted role of RNA and its partners in gene expression FEBS Lett 592(17), 2825-2827
      Pubmed
    • L. Landvogt, J.A. Ruland, C. Montellese, J. P. Siebrasse, U. Kutay and U. Kubitscheck (2018) Observing and tracking single small ribosomal subunits in vivo Methods Epub ahead of print
      Pubmed
    • S. Bhullar, C. Denby Wilkes, O. Arnaiz, M. Nowacki, L. Sperling and E. Meyer (2018) A mating-type mutagenesis screen identifies a zinc-finger protein required for specific DNA excision events in Paramecium Nucleic Acids Res Epub ahead of print
      Pubmed
    • A. J. Rzepiela, S. Ghosh, J. Breda, A. Vina-Vilaseca, A.P. Syed, A. J. Gruber, K. Eschbach, C. Beisel, E. van Nimwegen and M. Zavolan (2018) Single-cell mRNA profiling reveals the hierarchical response of miRNA targets to miRNA induction Mol Syst Biol 14(8), e8266
      Pubmed
    • L. Wyss, M. Waser, J. Gebetsberger, M. Zywicki and N. Polacek (2018) mRNA-specific translation regulation by a ribosome-associated ncRNA in Haloferax volcanii Sci Rep 8(1), 12502
      Pubmed
    • A. Jawaid, B. T. Woldemichael, E. A. Kremer, F. Laferriere, N. Gaur, T. Afroz, M. Polymenidou and I. M. Mansuy (2018) Memory Decline and Its Reversal in Aging and Neurodegeneration Involve miR-183/96/182 Biogenesis Mol Neurobiol Epub ahead of print
      Pubmed
    • P. J. Boersema, A. Melnik, B. P. C. Hazenberg, M. Rezeli, G. Marko-Varga, J. Kamiie, E. Portelius, K. Blennow, R. A. Zubarev, M. Polymenidou and P. Picotti (2018) The Biology and Disease-driven Initiative on Protein Aggregation Diseases of the Human Proteome Project: Goals and Progress to Date J Proteome Res Epub ahead of print 
      Pubmed
    • M. Jia, H. Gut and J. A. Chao (2018) Structural basis of IMP3 RRM12 recognition of RNA RNA Epub ahead of print 
      Pubmed
    • E. Kummer, M. Leibundgut, O. Rackham, R. G. Lee, D. Boehringer, A. Filipovska and N. Ban (2018) Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM Nature 560(7717), 263-267
      Pubmed
    • H. L. Lightfoot, T. Hagen, A. Clery, F. H. Allain and J. Hall (2018) Control of the polyamine biosynthesis pathway by G2-quadruplexes Elife 7, e36362 
      Pubmed
    • E. I. Kessi-Perez, F. Salinas, J. Molinet, A. Gonzalez, S. Muniz, J. M. Guillamon, M. N. Hall, L. F. Larrondo and C. Martinez (2018) Indirect monitoring of TORC1 signalling pathway reveals molecular diversity among different yeast strains Yeast Epub ahead of print 
      Pubmed
    • E. Lekka and J. Hall (2018) Non-coding RNAs in Disease FEBS Lett Epub ahead of print
      Pubmed
    • M. G. Mostofa, M. A. Rahman, N. Koike, A. M. Yeasmin, N. Islam, T. M. Waliullah, S. Hosoyamada, M. Shimobayashi, T. Kobayashi, M. N. Hall and T. Ushimaru (2018) CLIP and cohibin separate rDNA from nucleolar proteins destined for degradation by nucleophagy J Cell Biol Epub ahead of print
      Pubmed
    • M. van de Waterbeemd, S. Tamara, K.L. Fort, E. Damoc, V. Franc, P. Bieri, M. Itten, A. Makarov, N. Ban and A.J.R. Heck (2018) Dissecting ribosomal particles throughout the kingdoms of life using advanced hybrid mass spectrometry methods Nat Commun 9(2), 2493
      Pubmed
    • T. Wiegand, R. Cadalbert, C. von Schroetter, F.H. Allain and B. H. Meier, B (2018) Segmental isotope labelling and solid-state NMR of a 12 x 59 kDa motor protein: identification of structural variability J Biomol NMR Epub ahead of print
      Pubmed
    • D. G. Vitali, S. Käser, A. Kolb, K. S. Dimmer, A. Schneider and D. Rapapory (2018) Independent evolution of functionally exchangeable mitochondrial outer membrane import complexes Elife 7, 34488 
      Pubmed
    • F. Lampert, D. Stafa, A. Goga, M. V. Soste, S. Gilberto, N. Olieric, P. Picotti, M. Stoffel and M. Peter (2018) The multi-subunit GID/CTLH E3 ligase promotes proliferation and targets the transcription factor Hbp1 for degradation Elife 7, e35528 
      Pubmed
    • E.D. Karousis and O. Mühlemann (2018) Nonsense-Mediated mRNA Decay Begins Where Translation Ends Cold Spring Harb Perspect Biol Epub ahead of print 
      Pubmed
    • N. Savic, F.C. Ringnalda, H. Lindsay, C. Berk, K. Bargsten, Y. Li, D. Neri, M.D. Robinson, C. Ciaudo, J. Hall, M. Jinek and G. Schwank (2018) Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair Elife 7, e33761
      Pubmed
    • M. Polymenidou (2018) The RNA face of phase separation Science 360(6391) 859-860
      Pubmed
    • T. Iki, A. Cléry, N. Bologna, A. Sarazin, C. Brosnan, N. Pumplin, F.H.T. Allain and O. Voinnet (2018) Structural Flexibility Enables Alternative Maturation, ARGONAUTE Sorting and Activities of miR168, a Global Gene Silencing Regulator in Plants Mol Plant, Epub ahead of print
      Pubmed
    • V. Ostapcuk, F. Mohn, S.H. Carl, A. Basters, D. Hess, V. Iesmantavicius, L. Lampersberger, M. Flemr, A. Pandey, N.H. Thoma, J. Betschinger and M. Bühler (2018) Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes Nature 557(7707), 739-743
      Pubmed
    • C. Sellier, E. Cerro-Herreros, M. Blatter, F. Freyermuth, A. Gaucherot, F. Ruffenach, P. Sarkar, J. Puymirat, B. Udd, J. W. Day, G. Meola, G. Bassez, H. Fujimura, M. P. Takahashi, B. Schoser, D. Furling, R. Artero, F. H. T. Allain, B. Llamusi and N. Charlet-Berguerand (2018) rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences Nat Commun 9(1), 2009 
      Pubmed
    • D. C. Swarts and M. Jinek (2018) Cas9 versus Cas12a/Cpf1: Structure-function comparisons and implications for genome editing Wiley Interdiscip Rev RNA, e1481 
      Pubmed
    • P. Knuckles and M. Bühler (2018) Adenosine methylation as a molecular imprint defining the fate of RNA FEBS Lett, Epub ahead of print  
      Pubmed
    • W. Ahmed and J. Lingner (2018) PRDX1 and MTH1 cooperate to prevent ROS-mediated inhibition of telomerase Genes Dev,  32(9-10), 658-669
      Pubmed
    • P. Kumari, F. Aeschimann, D. Gaidatzis, J.J. Keusch, P. Ghosh, A. Neagu, K. Pachulska-Wieczorek, J.M. Bujnicki, H. Gut, H. Grosshans and R. Ciosk (2018) Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition Nat Commun, 9(1), 1549
      Pubmed
    • M. Kornete, R. Marone and L.T. Jeker (2018) Highly Efficient and Versatile Plasmid-Based Gene Editing in Primary T Cells J Immunol, 200(7), 2489-2501
      Pubmed
    • A.J. Gruber, R. Schmidt, S. Ghosh, G. Martin, A.R. Gruber, E. van Nimwegen and M. Zavolan (2018) Discovery of physiological and cancer-related regulators of 3' UTR processing with KAPAC Genome Biol, 19(1), 44
      Pubmed
    • S. Käser, I. Glauser, J. Rettig and A. Schneider (2018) The pseudo-dimeric tyrosyl-tRNA synthetase of T. brucei aminoacylates cytosolic and mitochondrial tRNA(Tyr) and requires both monomeric units for activity Mol Biochem Parasitol, 221, 52-55
      Pubmed
    • F. Michelini, A.P. Jalihal, S. Francia, C. Meers, Z.T. Neeb, F. Rossiello, U. Gioia, J. Aguado, C. Jones-Weinert, B. Luke, G. Biamonti, M. Nowacki, F. Storici, P. Carninci, N.G. Walter and F. d'Adda di Fagagna (2018) From "Cellular" RNA to "Smart" RNA: Multiple Roles of RNA in Genome Stability and Beyond Chem Rev,  118(8), 4365-4403
      Pubmed
    • B. Uszczynska-Ratajczak, J. Lagarde, A. Frankish, R. Guigo and R. Johnson (2018) Towards a complete map of the human long non-coding RNA transcriptome Nat Rev Genet, Epub ahead of print
      Pubmed
    • S. Boeynaems, S. Alberti, N.L. Fawzi, T. Mittag, M. Polymenidou, F. Rousseau, J. Schymkowitz, J. Shorter, B. Wolozin, L. Van Den Bosch, P. Tompa and M. Fuxreiter (2018) Protein Phase Separation: A New Phase in Cell Biology Trends Cell Biol, 28(6), 420-435
      Pubmed
    • G. Brancati and H. Grosshans (2018) An interplay of miRNA abundance and target site architecture determines miRNA acticity and specificity Nucleic Acids Res, Epub ahead of print
      NAR (Open Access)
    • K. Kobayashi, A. Jomaa, J.H. Lee, S. Chandrasekar, D. Boehringer, S.O. Shan and N. Ban (2018) Structure of a prehandover mammalian ribosomal SRP*SRP receptor targeting complex Science, 360(6386), 323-327
      Pubmed
    • S.K. Hindupur, M. Colombi, S.R. Fuhs, M.S. Matter, Y. Guri, K. Adam, M. Cornu, S. Piscuoglio, C.K.Y. Ng, C. Betz, D. Liko, L. Quagliata, S. Moes, P. Jenoe, L.M. Terracciano, M. H. Heim, T. Hunter and M.N. Hall (2018) The protein histidine phosphatase LHPP is a tumour suppressor Nature, 555(7698), 678-682
      Pubmed
    • C. Hoehener, I. Hug and M. Nowacki (2018) Dicer-like Enzymes with Sequence Cleavage Preferences Cell, 173(1), 234-247 e7
      Pubmed
    • P. Knuckles, T. Lence, I.U. Haussmann, D. Jacob, N. Kreim, S.H. Carl, I. Masiello, T. Hares, R. Villasenor, D. Hess, M.A. Andrade-Navarro, M. Biggiogera, M. Helm, M. Soller, M. Bühler and J.Y. Roignant (2018) Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m(6)A machinery component Wtap/Fl(2)d Genes Dev, 32(5-6), 415-429
      Pubmed
    • C. Dimitrakopoulos, S. Kumar Hindupur, L. Hafliger, J. Behr, H. Montazeri, M.N. Hall and N. Beerenwinkel (2018) Network-based integration of multi-omics data for prioritizing cancer genes Bioinformatics, Epub ahead of print
      Pubmed
    • T. Brandmann, H. Fakim, Z. Padamsi, J.Y. Youn, A.C. Gingras, M.R. Fabian and Jinek, M. (2018) Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes EMBO J, 37(7), e97869
      Pubmed
    • G.R. Bantug, M. Fischer, J. Grahlert, M.L. Balmer, G. Unterstab, L. Develioglu, R. Steiner, R., L. Zhang, A. S. H. Costa, P. M. Gubser, A. V. Burgener, U. Sauder, J. Loliger, R. Belle, S. Dimeloe, J. Lötscher, A. Jauch, M. Recher, G. Honger, M.N. Hall, P. Romero, C. Frezza and C. Hess (2018) Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8(+) T Cells Immunity, 48(3), 542-555 e6
      Pubmed
    • M. de la Mata and H. Grosshans (2018) Turning the table on miRNAs Nat Struct Mol Biol, 25(3), 195-197
      Pubmed
    • E. Michel, O. Duss and F.H. Allain (2018) An Integrated Cell-Free Assay to Study Translation Regulation by Small Bacterial Noncoding RNAs Methods Mol Biol, 1737, 177-195 
      Pubmed
    • A. Scaiola, C. Pena, M. Weisser, D. Böhringer, M. Leibundgut, P. Klingauf-Nerurkar, S. Gerhardy, V.G. Panse and N. Ban (2018) Structure of a eukaryotic cytoplasmic pre-40S ribosomal subunit EMBO J 37(7), e98499 
      Pubmed
    • G. Masliah, C. Maris, S.L. König, M. Yulikov, F. Aeschimann, A.L. Malinowska, J. Mabille, J. Weiler, A. Holla, J. Hunziker, N. Meisner-Kober, B. Schuler, G. Jeschke and  F.H. Allain (2018) Structural basis of siRNA recognition by TRBP double-stranded RNA binding domains EMBO J, 37(6), e97089  
      Pubmed
    • A. Hoffmann, S. Käser, M. Jakob, S. Amodeo, C. Peitsch, J. Tyc, S. Vaughan, B. Zuber, A. Schneider and T. Ochsenreiter (2018) Molecular model of the mitochondrial genome segregation machinery in Trypanosoma brucei Proc Natl Acad Sci U S A, 115(8), E1809-E1818
      Pubmed
    • E. Stuttfeld, C.H. Aylett, S. Imseng, D. Boehringer, A. Scaiola, E. Sauer, M.N. Hall, T. Maier and N. Ban (2018) Architecture of the human mTORC2 core complex Elife, 7, e33101
      Pubmed
    • G. Glousker and J. Lingner (2018) When Telomerase Causes Telomere Loss Dev Cell, 44(3), 281-283
      Pubmed
    • Schneider A. (2018) Dihydrofolate reductase and membrane translocation: evolution of a classic experiment: Classic landmark papers, irrespective of their age, can teach students how best science is practiced and inspire new experiments EMBO Rep, 19(3),  e45692
      Pubmed
    • R.P. Ngondo, D. Cirera-Salinas, J. Yu, H. Wischnewski, M. Bodak, S. Vandormael-Pournin, A. Geiselmann, R. Wettstein, J. Luitz, M. Cohen-Tannoudji and C. Ciaudo (2018) Argonaute 2 Is Required for Extra-embryonic Endoderm Differentiation of Mouse Embryonic Stem Cells Stem Cell Reports, 10(2), 461-476
      Pubmed
    • M. Habibian, M. Yahyaee-Anzahaee, M. Lucic, E. Moroz, N. Martin-Pintado, L.D. Di Giovanni, J. C. Leroux, J. Hall, C. Gonzalez and M.J. Damha (2018) Structural properties and gene-silencing activity of chemically modified DNA-RNA hybrids with parallel orientation Nucleic Acids Res, 46(4), 1614-23
      Pubmed
    • M. Clerici, M. Faini, L.M. Muckenfuss, R. Aebersold and M. Jinek (2018) Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex Nat Struct Mol Biol, 25(2), 135-138
      Pubmed
    • P. Nicholson, A. Gkratsou, C. Josi, M. Colombo and O. Mühlemann (2018) Dissecting the functions of SMG5, SMG7 and PNRC2 in nonsense-mediated mRNA decay of human cells RNA, 24(4), 557-573
      Pubmed
    • P. Bieri, B.J. Greber and N. Ban (2018) High-resolution structures of mitochondrial ribosomes and their functional implications Curr Opin Struct Biol, 49, 44-53
      Pubmed
    • J. Willi, P. Küpfer, D. Evéquoz, G. Fernandez, A. Katz, C. Leumann and N. Polacek (2018) Oxidative stress damages rRNA inside the ribosome and differentially affects the catalytic center Nucleic Acids Res, 46(4), 1945-1957
      Pubmed
    • N.B. Milev and D. Gatfield (2018) Circadian Clocks and UPR: New Twists as the Story Unfolds Dev Cell, 44(1), 7-9
      Pubmed
    • F. Voigt, J. Eglinger and J. A. Chao (2018) Detection of the First Round of Translation: The TRICK Assay Methods Mol Biol, 1649, 373-384
      Pubmed
    • W. Ahmed and J. Lingner (2018) Impact of oxidative stress on telomere biology Differentiation 99,21-27
      Pubmed
    • M. Vlot, J. Houkes, S. J. A. Lochs, D. C. Swarts, P. Zheng, T. Kunne, P. Mohanraju, C. Anders, M. Jinek, J. van der Oost, M. J. Dickman and S. J. J. Brouns (2018) Bacteriophage DNA glucosylation impairs target DNA binding by type I and II but not by type V CRISPR-Cas effector complexes Nucleic Acids Res, 46(2), 873-885
      Pubmed
    • E. Sonnleitner, A. Wulf, S. Campagne, X. Y. Pei, M. T. Wolfinger, G. Forlani, K. Prindl, L. Abdou, A. Resch, F. H. Allain, B. F. Luisi, H. Urlaub and U. Blasi (2018) Interplay between the catabolite repression control protein Crc, Hfq and RNA in Hfq-dependent translational regulation in Pseudomonas aeruginosa Nucleic Acids Res, 46(3), 1470-1485
      Pubmed
    • Z. T. Neeb and M. Nowacki (2018) RNA-mediated transgenerational inheritance in ciliates and plants Chromosoma, 127(1), 19-27
      Pubmed
    • S. Reber, J. Mechtersheimer, S. Nasif, J. A. Benitez, M. Colombo, M. Domanski, D. Jutzi, E. Hedlund and M. D. Ruepp (2018) CRISPR-Trap: A clean approach for the generation of gene knockouts and gene replacements in human cells Mol Biol Cell, 29(2), 75-83
      Pubmed
    • S. Nasif, L. Contu and O. Mühlemann (2018) Beyond quality control: The role of nonsense-mediated mRNA decay (NMD) in regulating gene expression Semin Cell Dev Biol, 75, 78-87 
      Pubmed
    • J. Singer, H. J. Ruscheweyh, A. L. Hofmann, T. Thurnherr, F. Singer, N. C. Toussaint, C. K. Y. Ng, S. Piscuoglio, C. Beisel, G. Christofori, R. Dummer, M. N. Hall, W. Krek, M.P. Levesque, M. G. Manz, H. Moch, A. Papassotiropoulos, D. J. Stekhoven, P. Wild, T. Wust, B. Rinn and N. Beerenwinkel (2018) NGS-pipe: a flexible, easily extendable, and highly configurable framework for NGS analysis Bioinformatics, 34(1), 107-108
      Pubmed

    2017

    • S. Käser, M. Willemin, F. Schnarwiler, B. Schimanski, D. Poveda-Huertes, S. Oeljeklaus, B. Haenni, B. Zuber, B. Warscheid, C. Meisinger and A. Schneider (2017) Biogenesis of the mitochondrial DNA inheritance machinery in the mitochondrial outer membrane of Trypanosoma brucei PLoS Pathog, 13(12), e1006808
      Pubmed
    • F. Voigt, H. Zhang, X.A. Cui, D. Triebold, A.X. Liu, J. Eglinger, E.S. Lee, J. A. Chao and A. F. Palazzo (2017) Single-Molecule Quantification of Translation-Dependent Association of mRNAs with the Endoplasmic Reticulum Cell Rep, 21(13), 3740-3753
      Pubmed
    • M. Zavolan M. and A. Kanitz (2017) RNA splicing and its connection with other regulatory layers in somatic cell reprogramming Curr Opin Cell Biol, 52, 8-13
      Pubmed
    • M. Clerici, M. Faini, R. Aebersold and M. Jinek (2017) Structural insights into the assembly and polyA signal recognition mechanism of the human CPSF complex Elife, 6, e33111
      Pubmed
    • K. Essig, D. Hu, J. C. Guimaraes, D. Alterauge, S. Edelmann, T. Raj, J. Kranich, G. Behrens, A. Heiseke, S. Floess, J. Klein, A. Maiser, S. Marschall, M. Hrabe de Angelis, H. Leonhardt, C. F. Calkhoven, E. Noessner, T. Brocker, J. Huehn, A. B. Krug, M. Zavolan, D. Baumjohann and V. Heissmeyer (2017) Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells Immunity, 47 (6), 1067-1082 e12
      Pubmed
    • Y. Guri, M. Colombi, E. Dazert, S. K. Hindupur, J. Roszik, S. Moes, P. Jenoe, M. H. Heim, I. Riezman, H. Riezman and M. N. Hall (2017) mTORC2 Promotes Tumorigenesis via Lipid Synthesis Cancer Cell, 32 (6), 807-823 e12
      Pubmed
    • G. Palermo, C. G. Ricci, A. Fernando, R. Basak, M. Jinek, I. Rivalta, V. S. Batista and J. A. McCammon (2017) Protospacer Adjacent Motif-Induced Allostery Activates CRISPR-Cas9 J Am Chem Soc 139(45), 16028-16031
      Pubmed
    • S. Berry, S. Rosa, M. Howard, M. Bühler and C. Dean (2017) Disruption of an RNA-binding hinge region abolishes LHP1-mediated epigenetic repression Genes Dev, 31 (21), 2115-2120
      Pubmed
    • F. Tang, P. Zhang, P. Ye, C. A. Lazarski, Q. Wu, I. L. Bergin, T. P. Bender, M. N. Hall, Y. Cui, L. Zhang, T. Jiang, Y. Liu and P. Zheng (2017) A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1 in mice Elife, 6, e32497
      Pubmed
    • M. Zavolan and B. R. Graveley (2017) RNAs: dynamic and mutable Genome Biol, 18 (1), 226
      Pubmed
    • S. E. Allen and M. Nowacki (2017) Necessity Is the Mother of Invention: Ciliates, Transposons, and Transgenerational Inheritance Trends Genet, 33 (3), 197-207
      Pubmed
    • M. Sivaramakrishnan, K. D. McCarthy, S. Campagne, S. Huber, S. Meier, A. Augustin, T. Heckel, H. Meistermann, M. N. Hug, P. Birrer, A. Moursy, S. Khawaja, R. Schmucki, N. Berntenis, N. Giroud, S. Golling, M. Tzouros, B. Banfai, G. Duran-Pacheco, J. Lamerz, Y. Hsiu Liu, T. Luebbers, H. Ratni, M. Ebeling, A. Clery, S. Paushkin, A. R. Krainer, F. H. Allain and F. Metzger (2017) Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers Nat Commun, 8(1), 1476
      Pubmed
    • M. E. Hughes, K. C. Abruzzi, R. Allada, R. Anafi, A. B. Arpat, G. Asher, P. Baldi, C. de Bekker, D. Bell-Pedersen, J. Blau, S. Brown, M. F. Ceriani, Z. Chen, J. C. Chiu, J. Cox, A. M. Crowell, J. P. DeBruyne, D. J. Dijk, L. DiTacchio, F. J. Doyle, G. E. Duffield, J. C. Dunlap, K. Eckel-Mahan, K. A. Esser, G. A. FitzGerald, D. B. Forger, L. J. Francey, Y. H. Fu, F. Gachon, D. Gatfield, P. de Goede, S. S. Golden, C. Green, J. Harer, S. Harmer, J. Haspel, M. H. Hastings, H. Herzel, E. D. Herzog, C. Hoffmann, C. Hong, J. J. Hughey, J. M. Hurley, H. O. de la Iglesia, C. Johnson, S. A. Kay, N. Koike, K. Kornacker, A. Kramer, K. Lamia, T. Leise, S. A. Lewis, J. Li, X. Li, A. C. Liu, J. J. Loros, T. A. Martino, J. S. Menet, M. Merrow, A. J. Millar, T. Mockler, F. Naef, E. Nagoshi, M. N. Nitabach, M. Olmedo, D. A. Nusinow, L. J. Ptacek, D. Rand, A. B. Reddy, M. S. Robles, T. Roenneberg, M. Rosbash, M. D. Ruben, S. S. C. Rund, A. Sancar, P. Sassone-Corsi, A. Sehgal, S. Sherrill-Mix, D. J. Skene, K. F. Storch, J. S. Takahashi, H. R. Ueda, H. Wang, C. Weitz, P. O. Westermark, H. Wijnen, Y. Xu, G. Wu, S. H. Yoo, M. Young, E. E. Zhang, T. Zielinski and J. B. Hogenesch (2017) Guidelines for Genome-Scale Analysis of Biological Rhythms J Biol Rhythms, 32(5), 380-393
      Pubmed
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    • M. Polymenidou and D. W. Cleveland (2017) Biological Spectrum of Amyotrophic Lateral Sclerosis Prions Cold Spring Harb Perspect Med, 7(11),
      Pubmed
    • R. Gumienny, D. J. Jedlinski, A. Schmidt, F. Gypas, G. Martin, A. Vina-Vilaseca and M. Zavolan (2017) High-throughput identification of C/D box snoRNA targets with CLIP and RiboMeth-seq Nucleic Acids Res, 45(5), 2341-2353
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    • P. Bieri, M. Leibundgut, M. Saurer, D. Boehringer and N. Ban (2017) The complete structure of the chloroplast 70S ribosome in complex with translation factor pY EMBO J, 36(4), 475-486
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    • A. Harsman and A. Schneider (2017) Mitochondrial protein import in trypanosomes: Expect the unexpected Traffic, 18(2), 96-109
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    2016

    • J. Gebetsberger, L. Wyss, A. M. Mleczko, J. Reuther and N. Polacek (2016) A tRNA-derived fragment competes with mRNA for ribosome binding and regulates translation during stress RNA Biol, Epub ahead of print
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    • Y. Guri and M. N. Hall (2016) mTOR Signaling Confers Resistance to Targeted Cancer Drugs Trends Cancer, 2(11), 688-697
      Pubmed
    • J. Plassais, L. Lagoutte, S. Correard, M. Paradis, E. Guaguere, B. Hedan, A. Pommier, N. Botherel, M. C. Cadiergues, P. Pilorge, D. Silversides, M. Bizot, M. Samuels, C. Arnan, R. Johnson, C. Hitte, G. Salbert, A. Mereau, P. Quignon, T. Derrien and C. Andre (2016) A Point Mutation in a lincRNA Upstream of GDNF Is Associated to a Canine Insensitivity to Pain: A Spontaneous Model for Human Sensory Neuropathies PLoS Genet, 12(12), e1006482
      Pubmed
    • D. Benjamin, M. Colombi, S. K. Hindupur, C. Betz, H. A. Lane, M. Y. El-Shemerly, M. Lu, L. Quagliata, L. Terracciano, S. Moes, T. Sharpe, A. Wodnar-Filipowicz, C. Moroni and M. N. Hall (2016) Syrosingopine sensitizes cancer cells to killing by metformin Sci Adv, 2(12), e1601756
      Pubmed
    • E. Aeby, W. Ahmed, S. Redon, V. Simanis and J. Lingner (2016) Peroxiredoxin 1 Protects Telomeres from Oxidative Damage and Preserves Telomeric DNA for Extension by Telomerase Cell Rep, 17(12), 3107-3114
      Pubmed
    • M. Berge, S. Campagne, J. Mignolet, S. Holden, L. Theraulaz, S. Manley, F. H. Allain and P. H. Viollier (2016) Modularity and determinants of a (bi-)polarization control system from free-living and obligate intracellular bacteria Elife, 5, e20640
      Pubmed
    • A. Harsman, S. Oeljeklaus, C. Wenger, J. L. Huot, B. Warscheid and A. Schneider (2016) The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins Nat Commun, 7, 13707
      Pubmed
    • Y. Shimada, F. Mohn and M. Bühler (2016) The RNA-induced transcriptional silencing complex targets chromatin exclusively via interacting with nascent transcripts Genes Dev, 30(23), 2571-2580
      Pubmed
    • E. Gasser, H. C. Johannssen, T. Rulicke, H. U. Zeilhofer and M. Stoffel (2016) Foxa1 is essential for development and functional integrity of the subthalamic nucleus Sci Rep, 6, 38611
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    • J. C. Guimaraes and M. Zavolan (2016) Patterns of ribosomal protein expression specify normal and malignant human cells Genome Biol, 17(1), 236
      Pubmed
    • R. Denzler, S. E. McGeary, A. C. Title, V. Agarwal, D. P. Bartel and M. Stoffel (2016) Impact of MicroRNA Levels, Target-Site Complementarity, and Cooperativity on Competing Endogenous RNA-Regulated Gene Expression Mol Cell, 64(3), 565-579
      Pubmed
    • U. Brykczynska, E. Pecho-Vrieseling, A. Thiemeyer, J. Klein, I. Fruh, T. Doll, C. Manneville, S. Fuchs, M. Iazeolla, M. Beibel, G. Roma, U. Naumann, N. Kelley, E. J. Oakeley, M. Mueller, B. Gomez-Mancilla, M. Bühler, E. Tabolacci, P. Chiurazzi, G. Neri, T. Bouwmeester, F. P. Di Giorgio and B. D. Fodor (2016) CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations Stem Cell Reports, 7(6), 1059-1071
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    • M. Bolten, C. L. Delley, M. Leibundgut, D. Boehringer, N. Ban and E. Weber-Ban (2016) Structural Analysis of the Bacterial Proteasome Activator Bpa in Complex with the 20S Proteasome Structure, 24(12), 2138-2151
      Pubmed
    • X. Ding, W. Bloch, S. Iden, M. A. Ruegg, M. N. Hall, M. Leptin, L. Partridge and S. A. Eming (2016) mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation Nat Commun, 7, 13226
      Pubmed
    • G. Palermo, Y. Miao, R. C. Walker, M. Jinek and J. A. McCammon (2016) Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations ACS Cent Sci, 2(10), 756-763
      Pubmed
    • D. R. Driscoll, S. A. Karim, M. Sano, D. M. Gay, W. Jacob, J. Yu, Y. Mizukami, A. Gopinathan, D. I. Jodrell, T. R. Evans, N. Bardeesy, M. N. Hall, B. J. Quattrochi, D. S. Klimstra, S. T. Barry, O. J. Sansom, B. C. Lewis and J. P. Morton (2016) mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer Cancer Res, 76(23), 6911-6923
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    • M. M. Reimao-Pinto, R. A. Manzenreither, T. R. Burkard, P. Sledz, M. Jinek, K. Mechtler and S. L. Ameres (2016) Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila EMBO J, 35(22), 2417-2434
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    • M. B. Mobin, S. Gerstberger, D. Teupser, B. Campana, K. Charisse, M. H. Heim, M. Manoharan, T. Tuschl and M. Stoffel (2016) The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation Nat Commun, 7, 12848
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    • Q. Fu, R. R. Pandey, N. A. Leu, R. S. Pillai and P. J. Wang (2016) Mutations in the MOV10L1 ATP Hydrolysis Motif Cause piRNA Biogenesis Failure and Male Sterility in Mice Biol Reprod, 95(5), 103
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    • E. Moroz, S. H. Lee, K. Yamada, F. Halloy, S. Martinez-Montero, H. Jahns, J. Hall, M. J. Damha, B. Castagner and J. C. Leroux (2016) Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells Mol Ther Nucleic Acids, 5(9), e364
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    • D. Ustianenko, J. Pasulka, Z. Feketova, L. Bednarik, D. Zigackova, A. Fortova, M. Zavolan and S. Vanacova (2016) TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs EMBO J, 35(20), 2179-2191
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    • M. N. Hall (2016) TOR and paradigm change: cell growth is controlled Mol Biol Cell, 27(18), 2804-6
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    • T. S. Miki, S. H. Carl, M. B. Stadler and H. Grosshans (2016) XRN2 Autoregulation and Control of Polycistronic Gene Expresssion in Caenorhabditis elegans PLoS Genet, 12(9), e1006313
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    • D. Bar-Yaacov, I. Frumkin, Y. Yashiro, T. Chujo, Y. Ishigami, Y. Chemla, A. Blumberg, O. Schlesinger, P. Bieri, B. Greber, N. Ban, R. Zarivach, L. Alfonta, Y. Pilpel, T. Suzuki and D. Mishmar (2016) Mitochondrial 16S rRNA Is Methylated by tRNA Methyltransferase TRMT61B in All Vertebrates PLoS Biol, 14(9), e1002557
      Pubmed
    • P. Sledz and M. Jinek (2016) Structural insights into the molecular mechanism of the m6A writer complex Elife, 5, e18434
      Pubmed
    • L. Bammert, S. Jonas, R. Ungricht and U. Kutay (2016) Human AATF/Che-1 forms a nucleolar protein complex with NGDN and NOL10 required for 40S ribosomal subunit synthesis Nucleic Acids Res, 44(20), 9803-9820
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    • M. Menzi, U. Pradère, Y. Wang, M. Fischer, F. Baumann, M. Bigatti and J. Hall (2016) Site-Specific Labeling of MicroRNA Precursors: A Structure-Activity Relationship Study Chembiochem, 17(21), 2012-2017
      Pubmed
    • M. Roos, U. Pradere, R. P. Ngondo, A. Behera, S. Allegrini, G. Civenni, J. A. Zagalak, J. R. Marchand, M. Menzi, H. Towbin, J. Scheuermann, D. Neri, A. Caflisch, C. V. Catapano, C. Ciaudo and J. Hall (2016) A Small-Molecule Inhibitor of Lin28 ACS Chem Biol, 11(10), 2773-2781
      Pubmed
    • N. Larburu, C. Montellese, M. F. O'Donohue, U. Kutay, P. E. Gleizes and C. Plisson-Chastang (2016) Structure of a human pre-40S particle points to a role for RACK1 in the final steps of 18S rRNA processing Nucleic Acids Res, 44(17), 8465-78
      Pubmed
    • E. M. Hock and M. Polymenidou (2016) Prion-like propagation as a pathogenic principle in frontotemporal dementia J Neurochem, 138 Suppl 1, 163-83
      Pubmed
    • S. Desy, J. Mani, A. Harsman, S. Käser and A. Schneider (2016) TbLOK1/ATOM19 is a novel subunit of the noncanonical mitochondrial outer membrane protein translocase of Trypanosoma brucei Mol Microbiol, 102(3), 520-529
      Pubmed
    • P. Odermatt, J. Trub, L. Furrer, R. Fricker, A. Marti and D. Schümperli (2016) Somatic therapy of a mouse SMA model with a U7 snRNA gene correcting SMN2 splicing Mol Ther, 24(10), 1797-1805
      Pubmed
    • S. Käser, S. Oeljeklaus, J. Tyc, S. Vaughan, B. Warscheid and A. Schneider (2016) Outer membrane protein functions as integrator of protein import and DNA inheritance in mitochondria Proc Natl Acad Sci U S A, 113(31), E4467-75
      Pubmed
    • E. C. Swart, V. Serra, G. Petroni and M. Nowacki (2016) Genetic Codes with No Dedicated Stop Codon: Context-Dependent Translation Termination Cell, 166(3), 691-702
      Pubmed
    • H. Lindsay, A. Burger, B. Biyong, A. Felker, C. Hess, J. Zaugg, E. Chiavacci, C. Anders, M. Jinek, C. Mosimann and M. D. Robinson (2016) CrispRVariants charts the mutation spectrum of genome engineering experiments Nat Biotechnol, 34(7), 701-2
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    • S. Campagne, S. Dintner, L. Gottschlich, M. Thibault, M. Bortfeld-Miller, A. Kaczmarczyk, A. Francez-Charlot, F. H. Allain and J. A. Vorholt (2016) Role of the PFXFATG[G/Y] Motif in the Activation of SdrG, a Response Regulator Involved in the Alphaproteobacterial General Stress Response Structure 24 (8),1237-47
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    • J. Kang, E. P. Kusnadi, A. J. Ogden, R. J. Hicks, L. Bammert, U. Kutay, S. Hung, E. Sanij, R. D. Hannan, K. M. Hannan and R. B. Pearson (2016) Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription Oncotarget, 7(31), 48887-48904
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    • A. J. Gruber, R. Schmidt, A. R. Gruber, G. Martin, S. Ghosh, M. Belmadani, W. Keller and M. Zavolan (2016) A comprehensive analysis of 3' end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogeneous ribonucleoprotein C on cleavage and polyadenylation Genome Res, 26(8), 1145-59
      Pubmed
    • J. M. Pröpster, F. Yang, S. Rabbani, B. Ernst, F. H. Allain and M. Schubert (2016) Structural basis for sulfation-dependent self-glycan recognition by the human immune-inhibitory receptor Siglec-8 Proc Natl Acad Sci U S A, 113(29), E4170-9
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    • S. Reber, J. Stettler, G. Filosa, M. Colombo, D. Jutzi, S. C. Lenzken, C. Schweingruber, R. Bruggmann, A. Bachi, S. M. Barabino, O. Mühlemann and M. D. Ruepp (2016) Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants EMBO J, 35(14), 1504-21
      Pubmed
    • G. Martin and M. Zavolan (2016) Redesigning CLIP for efficiency, accuracy and speed Nat Methods, 13(6), 482-3
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    • O. Cohen-Fix and U. Kutay (2016) Editorial overview: The cell nucleus: Plastic, elastic and fantastic Curr Opin Cell Biol, 40, iv-v
      Pubmed
    • D. Albino, G. Civenni, C. Dallavalle, M. Roos, H. Jahns, L. Curti, S. Rossi, S. Pinton, G. D'Ambrosio, F. Sessa, J. Hall, C. V. Catapano and G. M. Carbone (2016) Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer Cancer Res, 76(12), 3629-43
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    • M. Krepl, A. Clery, M. Blatter, F. H. Allain and J. Sponer (2016) Synergy between NMR measurements and MD simulations of protein/RNA complexes: application to the RRMs, the most common RNA recognition motifs Nucleic Acids Res, 44(13), 6452-70
      Pubmed
    • H. Jorjani, S. Kehr, D. J. Jedlinski, R. Gumienny, J. Hertel, P. F. Stadler, M. Zavolan and A. R. Gruber (2016) An updated human snoRNAome Nucleic Acids Res, 44(11), 5068-82
      Pubmed
    • E. D. Karousis, S. Nasif and O. Mühlemann (2016) Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact Wiley Interdiscip Rev RNA, 7(5), 661-82
      Pubmed
    • R. Ungricht and U. Kutay (2016) A Wounded Nucleus Needs ESCRT Service Dev Cell, 37(3), 202-4
      Pubmed
    • O. Mühlemann (2016) Spermatogenesis Studies Reveal a Distinct Nonsense-Mediated mRNA Decay (NMD) Mechanism for mRNAs with Long 3'UTRs PLoS Genet, 12(5), e1005979
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    • R. Ungricht, S. Pawar and U. Kutay (2016) An In Vitro Assay to Study Targeting of Membrane Proteins to the Inner Nuclear Membrane Methods Mol Biol, 1411, 461-77
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    • A. Burger, H. Lindsay, A. Felker, C. Hess, C. Anders, E. Chiavacci, J. Zaugg, L. M. Weber, R. Catena, M. Jinek, M. D. Robinson and C. Mosimann (2016) Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes Development, 143(11), 2025-37
      Pubmed
    • P. Janich, A. B. Arpat, V. Castelo-Szekely and D. Gatfield (2016) Analyzing the temporal regulation of translation efficiency in mouse liver Genom Data, 8, 41-4
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    • J. Carlevaro-Fita, A. Rahim, R. Guigo, L. A. Vardy and R. Johnson (2016) Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells RNA, 22(6), 867-82
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    • H. Luidalepp, S. Berger, O. Joss, T. Tenson and N. Polacek (2016) Ribosome Shut-Down by 16S rRNA Fragmentation in Stationary-Phase Escherichia coli J Mol Biol, 428(10 Pt B), 2237-2247
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    • Y. V. Nikolaev, K. Kochanowski, H. Link, U. Sauer and F. H. Allain (2016) Systematic Identification of Protein-Metabolite Interactions in Complex Metabolite Mixtures by Ligand-Detected Nuclear Magnetic Resonance Spectroscopy Biochemistry, 55(18), 2590-600
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    • M. M. Swierczynska and M. N. Hall (2016) eIF4A moonlights as an off switch for TORC1 EMBO J, 35(10), 1013-4
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    • F. Grahammer, V. Nesterov, A. Ahmed, F. Steinhardt, L. Sandner, F. Arnold, T. Cordts, S. Negrea, M. Bertog, M. A. Ruegg, M. N. Hall, G. Walz, C. Korbmacher, F. Artunc and T. B. Huber (2016) mTORC2 critically regulates renal potassium handling J Clin Invest, 126(5), 1773-82
      Pubmed
    • B. J. Greber and N. Ban (2016) Structure and Function of the Mitochondrial Ribosome Annu Rev Biochem, 85, 103-132
      Pubmed
    • K. Drägert, I. Bhattacharya, M. N. Hall, R. Humar, E. Battegay and E. Haas (2016) Basal mTORC2 activity and expression of its components display diurnal variation in mouse perivascular adipose tissue Biochem Biophys Res Commun, 473(1), 317-22
      Pubmed
    • R. Janowski, G. A. Heinz, A. Schlundt, N. Wommelsdorf, S. Brenner, A. R. Gruber, M. Blank, T. Buch, R. Buhmann, M. Zavolan, D. Niessing, V. Heissmeyer and M. Sattler (2016) Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40 Nat Commun, 7, 11032
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    • C. Anders, K. Bargsten and M. Jinek (2016) Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9 Mol Cell, 61(6), 895-902
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    • V. Olieric, T. Weinert, A. D. Finke, C. Anders, D. Li, N. Olieric, C. N. Borca, M. O. Steinmetz, M. Caffrey, M. Jinek and M. Wang (2016) Data-collection strategy for challenging native SAD phasing Acta Crystallogr D Struct Biol, 72(Pt 3), 421-9
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    • C. Schweingruber, P. Soffientini, M. D. Ruepp, A. Bachi and O. Mühlemann (2016) Identification of Interactions in the NMD Complex Using Proximity-Dependent Biotinylation (BioID) PLoS One, 11(3), e0150239
      Pubmed
    • V. Romeo and D. Schümperli (2016) Cycling in the nucleus: regulation of RNA 3' processing and nuclear organization of replication-dependent histone genes Curr Opin Cell Biol, 40, 23-31
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    • M. Bodak and C. Ciaudo (2016) Monitoring Long Interspersed Nuclear Element 1 Expression During Mouse Embryonic Stem Cell Differentiation Methods Mol Biol, 1400, 237-59
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    • J. Y. Tan and A. C. Marques (2016) miRNA-mediated crosstalk between transcripts: The missing "linc"? Bioessays 38(3),295-301
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    • U. Pradère and J. Hall (2016) Site-Specific Difunctionalization of Structured RNAs Yields Probes for microRNA Maturation Bioconjug Chem, 27(3), 681-7
      Pubmed
    • A. Jomaa, D. Boehringer, M. Leibundgut and N. Ban (2016) Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon Nat Commun, 7, 10471
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    • L. Zhang, B. O. Tschumi, I. C. Lopez-Mejia, S. G. Oberle, M. Meyer, G. Samson, M. A. Ruegg, M. N. Hall, L. Fajas, D. Zehn, J. P. Mach, A. Donda and P. Romero (2016) Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner Cell Rep, 14(5), 1206-17
      Pubmed
    • E. Dazert, M. Colombi, T. Boldanova, S. Moes, D. Adametz, L. Quagliata, V. Roth, L. Terracciano, M. H. Heim, P. Jenoe and M. N. Hall (2016) Quantitative proteomics and phosphoproteomics on serial tumor biopsies from a sorafenib-treated HCC patient Proc Natl Acad Sci U S A, 113(5), 1381-6
      Pubmed
    • H. Richter, I. Katic, H. Gut and H. Grosshans (2016) Structural basis and function of XRN2 binding by XTB domains Nat Struct Mol Biol, 23(2), 164-171
      Pubmed
    • V. Albert, K. Svensson, M. Shimobayashi, M. Colombi, S. Munoz, V. Jimenez, C. Handschin, F. Bosch and M. N. Hall (2016) mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue EMBO Mol Med, 8(3), 232-46
      Pubmed
    • O. Niewoehner and M. Jinek (2016) Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6 RNA, 22(3), 318-29
      Pubmed
    • B. J. Greber, S. Gerhardy, A. Leitner, M. Leibundgut, M. Salem, D. Boehringer, N. Leulliot, R. Aebersold, V. G. Panse and N. Ban (2016) Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation Cell, 164(1-2), 91-102
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    • C. H. Aylett, E. Sauer, S. Imseng, D. Boehringer, M. N. Hall, N. Ban and T. Maier (2016) Architecture of human mTOR complex 1 Science, 351(6268), 48-52
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    • Z. Yang, K. M. Chen, R. R. Pandey, D. Homolka, M. Reuter, B. K. Janeiro, R. Sachidanandam, M. O. Fauvarque, A. A. McCarthy and R. S. Pillai (2016) PIWI Slicing and EXD1 Drive Biogenesis of Nuclear piRNAs from Cytosolic Targets of the Mouse piRNA Pathway Mol Cell, 61(1), 138-52
      Pubmed
    • M. Shimobayashi and M. N. Hall (2016) Multiple amino acid sensing inputs to mTORC1 Cell Res, 26(1), 7-20
      Pubmed
    • A. Neve, J. Trub, S. Saxena and D. Schümperli (2016) Central and peripheral defects in motor units of the diaphragm of spinal muscular atrophy mice Mol Cell Neurosci, 70, 30-41
      Pubmed
    • P. Shende, L. Xu, C. Morandi, L. Pentassuglia, P. Heim, S. Lebboukh, C. Berthonneche, T. Pedrazzini, B. A. Kaufmann, M. N. Hall, M. A. Ruegg and M. Brink (2016) Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy Cardiovasc Res, 109(1), 103-14
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    • B. Herkert, A. Kauffmann, S. Molle, C. Schnell, T. Ferrat, H. Voshol, J. Juengert, H. Erasimus, G. Marszalek, M. Kazic-Legueux, E. Billy, D. Ruddy, M. Stump, D. Guthy, M. Ristov, K. Calkins, S. M. Maira, W. R. Sellers, F. Hofmann, M. N. Hall and S. M. Brachmann (2016) Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition Cancer Res, 76(2), 390-402
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    • A. Brunschweiger, L. F. Gebert, M. Lucic, U. Pradere, H. Jahns, C. Berk, J. Hunziker and J. Hall (2016) Site-specific conjugation of drug-like fragments to an antimiR scaffold as a strategy to target miRNAs inside RISC Chem Commun (Camb), 52(1), 156-9
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    • J. Mani, C. Meisinger and A. Schneider (2016) Peeping at TOMs-Diverse Entry Gates to Mitochondria Provide Insights into the Evolution of Eukaryotes Mol Biol Evol, 33(2), 337-51
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    • K. Tugay, C. Guay, A. C. Marques, F. Allagnat, J. M. Locke, L. W. Harries, G. A. Rutter and R. Regazzi (2016) Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets Diabetologia, 59(1), 161-9
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    • R. Wettstein, M. Bodak and C. Ciaudo (2016) Generation of a Knockout Mouse Embryonic Stem Cell Line Using a Paired CRISPR/Cas9 Genome Engineering Tool Methods Mol Biol, 1341, 321-43
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    2015

    • L. Badertscher, T. Wild, C. Montellese, L. T. Alexander, L. Bammert, M. Sarazova, M. Stebler, G. Csucs, T. U. Mayer, N. Zamboni, I. Zemp, P. Horvath. and U. Kutay (2015) Genome-wide RNAi Screening Identifies Protein Modules Required for 40S Subunit Synthesis in Human Cells Cell Rep, 13 (12), 2879-91
      Pubmed
    • F. Aimi, S. Georgiopoulou, I. Kalus, F. Lehner, A. Hegglin, P. Limani, V. Gomes de Lima, A. R. M, M. N. Hall, N. Lindenblatt, E. Haas, E. J. Battegay and R. Humar (2015) Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult Sci Rep, 5, 17705
      Pubmed
    • O. Duss, N. Diarra Dit Konté and F. H. Allain (2015) Cut and Paste RNA for Nuclear Magnetic Resonance, Paramagnetic Resonance Enhancement, and Electron Paramagnetic Resonance Structural Studies Methods Enzymol, 565, 537-62
      Pubmed
    • E. Michel and F. H. Allain (2015) Selective Amino Acid Segmental Labeling of Multi-Domain Proteins Methods Enzymol, 565, 389-422
      Pubmed
    • L. Farine, M. Niemann, A. Schneider and P. Bütikofer (2015) Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei Sci Rep, 5, 16787
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    • J. A. Zagalak, M. Menzi, F. Schmich, H. Jahns, A. M. Dogar, F. Wullschleger, H. Towbin and J. Hall (2015) Properties of short double-stranded RNAs carrying randomized base pairs: toward better controls for RNAi experiments RNA, 21(12), 2132-42
      Pubmed
    • S. I. Duque, W. D. Arnold, P. Odermatt, X. Li, P. N. Porensky, L. Schmelzer, K. Meyer, S. J. Kolb, D. Schümperli, B. K. Kaspar and A. H. Burghes (2015) A large animal model of spinal muscular atrophy and correction of phenotype Ann Neurol, 77(3), 399-414
      Pubmed
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    2014

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