Von Molekülen zu Medikamenten

The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA
Advances in genome editing through control of DNA repair pathways
Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth
CASPR, an analysis pipeline for single and paired guide RNA CRISPR screens, reveals optimal target selection for long noncoding RNAs
Structural basis of a small molecule targeting RNA for a specific splicing correction
Editorial overview: Protein-nucleic acid interactions - cryo-EM, what else?
PolyASite 2.0: a consolidated atlas of polyadenylation sites from 3' end sequencing
Structure and functional implications of WYL domain-containing bacterial DNA damage response regulator PafBC
The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing
Recent advances in understanding bacterial and archaeoeukaryotic primases
The molecular mechanism of cotranslational membrane protein recognition and targeting by SecA