Largest study of developmental microRNA dynamics uncovers mechanism of their regulation

FMI researchers profiled the expression of more than 150 miRNAs as C. elegans larvae developed into adult worms. Image credits: Nahar, Morales Moya, et al. Nucleic Acids Research

FMI News Article
Gene expression is controlled by numerous small RNA molecules called microRNAs, or miRNAs. However, specific functions of most miRNAs remain poorly understood. Working in worms, FMI researchers created an encyclopedia of miRNA dynamics during development, uncovering mechanisms of their regulation. The findings help to better understand typical development and may reveal how these tiny molecules contribute to disease when they become dysfunctional.

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Read the Publication in Nucleic Acids Research (Open Access)

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