News Listing

The Allain lab (ETH Zurich) together with the Sponer (Czech Academy of Sciences, Brno, Czech Republic) and Zavolan (University of Basel) labs joined forces to gain insight into the RNA binding mode of RRM1 of SRSF1. Based on the complex structure, it was possible to engineer by mutating a single…

The labs of Norbert Polacek and André Schneider (Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern) discovered that in Trypanosoma brucei upon nutritional stress tRNAs get shortened so that they can not be used for translation, which leads to reduction of…

This week's edition of "Puls", the Swiss television's (SRF) health magazine, focused this week on Corona vaccination. The edition featured a video on mRNA vaccines featuring Steve Pascolo. Steve Pascolo is group leader at the Dermatology Clinic of the University Hospital Zurich, head of the URPP…

The fourteenth edition of the NCCR RNA & Disease Newsletter -The Messenger has been published.

Click here to read The Messenger

FMI News Article
Just like people, cells get stressed too. A sudden drop in oxygen, overheating, or toxins can trigger a cascade of molecular changes that lead cells to stop growing, produce stress-protective factors, and form stress granules – proteins and RNA molecules huddled together into…

The lab of Jonathan Hall in collaboration with Mihaela Zavolan's lab investigated the targetome of two miRNAs using a new class of miR-CLIP probes. They found that the two isoforms miR-124 have a different inhibitory effect on a given target. Their findings have been published in an article entitled…

The labs of Ana Claudia Marques and Constance Ciaudo investigated the requirement of translation for miRNA mediated RNA decay. Their paper entitled "Translation is required for miRNA-dependent decay of endogenous transcripts" has been published in EMBO Reports.

Synopsis
Evidence that…

This week Emmanuelle Charpentier and Jennifer Doudna receive the 2020 Nobel Prize in Chemistry "for the development of a method for genome editing" and in 2006 the Nobel Prize in Physiology or Medicine was awarded to Andrew Fire and Craig Mello for “for their discovery of RNA interference – gene…

Interview UZH News
According to Isabelle Mansuy’s research, the epigenome – which can switch our genes on and off – can be modified, positively or negatively, by our lifestyle choices. At least some of these modifications are passed down through the generations.

Link to Interview UZH News

"Gesundh…

Welcome to Alex Schier as a new associate member of the NCCR RNA & Disease.