National Center of Competence
in Research, RNA & Disease

News Listing

Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs

The Pillai lab identified that NUDT12 is a decapping enzyme of NAD-capped RNAs in the cytoplasm and forms a complex with BLMH, which is responsible for the localization of the complex. Their findings were published in Cell Reports.

Highlights

  • Human NUDT12 is a decapping enzyme for NAD-capped RNAs
  • ...
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NCCR Newsletter No. 12

The twelfth edition of the NCCR RNA & Disease Newsletter -The Messenger has been published.

Click here to read The Messenger

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A new druggable step in the gene expression pathway

FMI News Article
Thanks to their expertise in single-molecule imaging of RNAs, researchers from the group of Jeff Chao at the FMI helped to reveal the biological mechanism of a small molecule that restricts Ewing’s sarcoma cell growth. The study - published in Nature Chemical Biology - is further...

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Apply Now: Bench2Biz Workshop 2019 - from cutting-edge research to entrepreneurship

Are you wondering if your invention/research is commercializable? Do you need to get a clear picture on how to pursue your business idea? Would you benefit from personalized guidance from experts? The Bench2biz workshop 2019 taking place in Zurich for aspiring entrepreneurs in science & technology...

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Swiss RNA Workshop 2020: Registration Open

The 21st edition of the Swiss RNA Workshop will take place on January 24, 2020 at the University of Bern, UniS, A003 starting at 09:15.

This year's keynotes will be delivered by Reinhard Lührmann (MPI for Biophysical Chemistry, Göttingen, Germany, Lab Website) and Nicholas Luscombe (Francis Crick...

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PolyASite 2.0: a consolidated atlas of polyadenylation sites from 3' end sequencing

The Zavolan updated their PolyASite web resource, which is based on a curated dataset of polyadenylation sites in human, mouse and worm genomes.The publication describing the update went online at Nucleic Acids Research.

Abstract:
Generated by 3' end cleavage and polyadenylation at alternative...

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Insights into posttransciptional regulation of metabolism

The Stoffel lab (ETH Zurich) in collaboration with the Tuschl lab (Rockefeller University) discovered that the RNA binding protein A1CF regulates the activities of important metabolic enzymes through controlling which of the alternatively spliced isoforms is expressed. The publication entitled "The...

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How to construct a protein factory

Press Release / Medienmitteilung Universität Bern
The complexity of molecular structures in the cell is amazing. Having achieved great success in elucidating these structures in recent years, biologists are now taking on the next challenge: to find out more about how they are constructed. A joint...

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Recent progress in studying the molecular machines involved in mRNA 3'-end processing

A Current Opinion in Structural Biology article by the labs of Martin Jinek and Lori Passmore discusses recent advances made in gaining mechanistic insights into mRNA 3'-end processing. The article is part of a themed issue on protein nucleic acid interactions edited by Frédéric Allain and Martin...

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Horizons Magazine Debate: Is writing a doctorate a normal job?

They’re pursuing their passions, and can delve deeply into their chosen topic. Should doctoral students be able to regard their research as a regular job?

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