Susan Gottesmann - NCCR Seminar Series (BE)

Intermembrane space-localized TbTim15 is an essential subunit of the single mitochondrial inner membrane protein translocase of trypanosomes
A highly optimized human in vitro translation system
A highly conserved tRNA modification contributes to C. albicans filamentation and virulence
Neutrophil proteases are protective against SARS-CoV-2 by degrading the spike protein and dampening virus-mediated inflammation
Buffer Choice and pH Strongly Influence Phase Separation of SARS-CoV-2 Nucleocapsid with RNA
The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design

Recent Preprints

A protein condensation network contextualises cell fate decisions
A functional screen uncovers circular RNAs regulating excitatory synaptogenesis in hippocampal neurons
SP110 sequestration of SP100 protects against toxic filaments during innate immune signaling
ChAHP2 and ChAHP control diverse retrotransposons by complementary activities
Codon Pair-Specific Translation Defects Trigger Ribosome-Associated Quality Control to Avoid Proteotoxic Stress