Joshua Mendell - NCCR RNA Seminar Series (ZH)

Analysing the effect of full-length and C-terminally truncated progranulin on proliferation, colony formation, and migration in HepG2 and U87 cells
Imaging the cytoplasmic lives of single mRNAs
Photoswitchable RNA Degraders for Spatiotemporal Activation of Host-Directed Antivirals in Mammalian Cells
Identification of transglutaminase 2 mediated polyaminated proteins in a hepatocellular cancer cell line
Establishment of an imaging-based screening pipeline for the identification of human ribosome biogenesis inhibitors

Recent Preprints

The Bone Morphogenetic Pathway Controls the Uptake of Infectious Prions
Dystonia-associated Torsins sustain CLCC1 function to promote membrane fusion of the nuclear envelope for NPC biogenesis
Germline-limited transposon remnants foster somatic genome diversification
Quantitative comparison of methodologies for translation site imaging in living cells
Directed evolution of compact RNA-guided nucleases for homology–directed repair in mammalian cells