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Logo NCCR RNA & Disease
National Center of Competence
in Research, RNA & Disease
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RNA-DECO: Decorating RNA for a purpose

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Events

25 January 2021 16:00 – 17:00

Roy Parker - NCCR Seminar Series (Zoom)

Zoom

Canceled

Swiss RNA Workshop 2021

Due to restrictions for events imposed due to the Covid-19 pandemic, the Swiss RNA [...]

Canceled

NCCR RNA & Disease Kandersteg Retreat 2021

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News

20/01/2021

From structure to function: A single amino acid substitution in RRM1 of SRSF1 leads to SMN2 exon 7 inlcusion

08/01/2021

Translational Control by Reversible tRNA Length Changes in Trypanosomes

06/01/2021

SRF Health Magazine "Puls" Video on mRNA Vaccines featuring Steve Pascolo

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Recent Publications

  • Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing
  • tRNA 3' shortening by LCCR4 as a response to stress in Trypanosoma brucei
  • RNA antitoxin SprF1 binds ribosomes to attenuate translation and promote persister cell formation in Staphylococcus aureus
  • Surface tensiometry of phase separated protein and polymer droplets by the sessile drop method
  • Gene Expression Signatures of a Preclinical Mouse Model during Colorectal Cancer Progression under Low-Dose Metronomic Chemotherapy

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Recent Preprints

  • Dynamics of gene expression and chromatin marking during cell state transition
  • Susceptibility of well-differentiated airway epithelial cell cultures from domestic and wildlife animals to SARS-CoV-2
  • SF3B1 promotes tumor malignancy through splicing-independent co-activation of HIF1alpha
  • SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility
  • Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome

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Swiss National Science Foundation (SNSF)
Leading House
Universität Bern
Co-Leading House
ETH Zürich
Affiliated Institutions
École polytechnique fédérale de Lausanne
Friedrich Miescher Institute for Biomedical Research
Universität Basel
Universität Luzern
Universität Zürich
Université de Genève